Location:San Diego, CA 92121
Position type: Full time
Job Code: KB-Chem
Required education: Ph.D. Degree /Master’s Degree
Area(s) of expertise desired: Organic Chemistry, Medicinal Chemistry

Description
Kumquat Biosciences is committed to the discovery and development of innovative drugs to transform cancer treatments. Kumquat brings together an accomplished management team and distinguished scientific founder to translate innovative research to novel therapeutics.  Our team has a proven track record of drug discovery and development, having played pivotal roles in the discovery of multiple clinical-stage compounds as well as approved drug for the treatment of cancer and immune-mediated inflammatory diseases.

We are currently seeking a highly motivated, creative Principal Scientist or Senior Scientist to join our experienced drug discovery and drug development team in San Diego. This candidate will report to the Director of chemistry and work closely with members within chemistry, biology and DMPK team to drive discovery research programs into clinical development while providing scientific and technical expertise.  This is a hands-on position with responsibility for the design, synthesis, analysis and characterization of small molecule compounds.  The ideal candidate will have practical experience in aspects of organic chemistry and medicinal chemistry with relevant industrial experience.  A strong team player who enjoys scientific discovery and has the ability to communicate and collaborate in an interdisciplinary environment is essential. The candidate will have the opportunity to work on multiple programs within the company’s pipeline which comprises potentially first-in class approaches & novel-novel targets.

Role responsibilities
Design compounds based on structural biology and SAR knowledge

Execute synthetic routes to prepare small molecule compounds for evaluation

Document, organize and interpret experimental data

Collaborate with project team leaders and provide chemical expertise

Present at group and company program meetings

Contribute to a fast-paced, dynamic, data-driven scientific culture that embraces innovation and excellence

Qualifications
Ph.D. in synthetic organic or medicinal chemistry with minimum 5 years industrial experience or M.S. in organic chemistry with minimum 10 years industrial experience

Strong experience in structure-based drug design methods and applications

Familiarity with relevant biological and DMPK disciplines and the ability to integrate these disciplines into the structure based design of new bioactive compounds

Proven track record of delivery of small molecule therapeutic candidates in the pharmaceutical industry

Track record of accomplishment in medicinal chemistry as evidenced by quality and quantity of publications/inventions

Strong written and communication skills, good problem solving abilities, and an ability to work effectively with a diverse team of co-workers in a dynamic environment

Kumquat Biosciencesoffers an attractive salary and benefits package, including equity incentives.  To apply, please submit your resume to careers@kumquatbio.com